The Manifesto about women in STEM offers 50 texts aimed at the entire population. It brings together the thoughts of several authors and groups from schools, universities and the private sector who work on women in STEM in the Canadian Francophonie. This Manifesto aims to be positive and impactful, even if there is still some way to go towards equity and parity. Several major issues remain relevant, such as work-family balance and maternity without penalty. Issues such as intersectionality, EDI (equity, diversity and inclusion) and the impact of the COVID-19 pandemic on women in STEM are also explored.